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KMID : 1007420210190020064
Mood and Emotion
2021 Volume.19 No. 2 p.64 ~ p.73
Predictors of 1-Year Rehospitalization for Patients with Major Depressive Disorder: A Retrospective Study in a University Hospital
Yoo Ji-Min

Kim Sung-Min
Um Yoo-Hyun
Kim Tae-Won
Seo Ho-Jun
Hong Seung-Chul
Jeong Jong-Hyun
Abstract
Background: This study aimed to assess the clinical characteristics of patients with major depressive disorder who were rehospitalized within 1 year and to determine whether the 1-year rehospitalization rate varied depending on the type of medication and treatment method.

Methods: Clinical characteristics of 531 patients hospitalized for major depressive disorder were assessed. The use and type of antidepressants, antipsychotics, mood stabilizers, and hypnotics were also evaluated.

Results: Of the 531 subjects, 68 (12.8%) were rehospitalized within a year. The number of past depressive episodes (1.56¡¾2.67 vs. 0.90¡¾1.18) (p=0.048) and the number of previous psychiatric hospitalizations (0.82¡¾1.93 vs. 0.29¡¾0.83 times) (p=0.029) were high in the 1-year rehospitalization group. The rate of family history of mood disorder (25.0% vs. 13.6%) (p=0.014) and the rate of comorbid personality disorder (16.2% vs. 8.6%) (p=0.049) were also high in the 1-year rehospitalization group. Multiple logistic regression analysis showed that the number of previous psychiatric hospitalizations affected the rate of 1-year rehospitalization (p=0.003).

Conclusion: The number of previous psychiatric hospitalizations could be used to predict rehospitalizations of patients with major depressive disorder within 1 year. In addition, family history of mood disorders and comorbidity of personality disorders may affect rehospitalization of such patients.
KEYWORD
Major depressive disorder, Patient readmission, Antidepressants
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